| Consistory of 1534.12.18 (at the time of creation) (2) |
| 1. |  Mr. Alessandro Farnese (14), Apostolic Administrator of Parma (Italy) | Cardinal-Deacon |
| 2. | Mr. Guido Ascanio Sforza di Santa Fiora (15), Apostolic Administrator of Montefiascone (Italy) and Apostolic Administrator of Corneto (Italy) | Cardinal-Deacon |
| Consistory of 1535.05.21 (at the time of creation) (7) |
| 1. |  Archbishop Nikolaus von Schönberg, O.P. (62), Metropolitan Archbishop of Capua (Italy) | Cardinal-Priest |
| 2. |  Bishop Girolamo Ghinucci (55), Bishop of Worcester (England) and Apostolic Administrator of Malta (Malta) | Cardinal-Priest |
| 3. | Bishop Giacomo Simoneta (60), Bishop of Pesaro (Italy) | Cardinal-Priest |
| 4. |  Bishop John Fisher (66), Bishop of Rochester (England) | Cardinal-Priest |
| 5. |  Bishop Jean du Bellay (43), Bishop of Paris (France) | Cardinal-Priest |
| 6. | Mr. Gasparo Contarini (51) | Cardinal-Deacon |
| (7) |  Fr. Marino Ascanio Caracciolo (67), Bishop emeritus of Catania (Italy) | Cardinal-Deacon |
| Consistory of 1536.12.22 (at the time of creation) (11) |
| 1. |  Archbishop Gian Pietro Carafa (60), Apostolic Administrator of Acerra (Italy) and Metropolitan Archbishop emeritus of Brindisi–Oria (Italy) | Cardinal-Priest |
| 2. | Archbishop Giovanni Maria Ciocchi del Monte (49), Metropolitan Archbishop of Manfredonia (Italy) | Cardinal-Priest |
| 3. | Bishop Ennio Filonardi (70), Bishop of Veroli (Italy) | Cardinal-Priest |
| 4. | Bishop Jacopo Sadoleto (59), Bishop of Carpentras (France) | Cardinal-Priest |
| 5. | Bishop Cristoforo Giacobazzi, Bishop of Cassano all’Jonio (Italy) and Datary of His Holiness of Apostolic Dataria | Cardinal-Priest |
| 6. | Bishop Charles de Hémard de Denonville (43), Bishop of Mâcon (France) | Cardinal-Priest |
| 7. | Bishop Rodolfo Pio (36), Bishop of Faenza (Italy) | Cardinal-Priest |
| 8. | Mr. Reginald Pole (36) | Cardinal-Deacon |
| 9. |  Mr. Rodrigo Luis de Borja y de Castre-Pinós (12) | Cardinal-Deacon |
| (10) | Archbishop Girolamo Aleandro (56), Metropolitan Archbishop of Brindisi–Oria (Italy) | Cardinal-Priest |
| (11) | Mr. Niccolò Caetani (10) | Cardinal-Deacon |
| Consistory of 1538.10.18 (at the time of creation) (1) |
| 1. | Archbishop Pedro Sarmiento (60), Metropolitan Archbishop of Santiago de Compostela (Spain) | Cardinal-Priest |
| Consistory of 1538.12.20 (at the time of creation) (6) |
| 1. | Bishop Juan Álvarez de Toledo, O.P. (50), Bishop of Burgos (Spain) | Cardinal-Priest |
| 2. | Bishop Pedro Fernández Manrique (38), Bishop of Córdoba (Spain) | Cardinal-Priest |
| 3. | Bishop Robert de Lenoncourt (53), Bishop of Châlons-sur-Marne (France) | Cardinal-Priest |
| 4. |  Archbishop David Beaton (44), Bishop of Mirepoix (France) and Coadjutor Archbishop of Saint Andrews (Scotland) | Cardinal-Priest |
| (5) |  Fr. Ippolito d’Este (Hillpolyte d’Este-Ferrare) (29), Apostolic Administrator of Milano (Italy) | Cardinal-Deacon |
| (6) | Mr. Pietro Bembo, S.M.O.M. (68) | Cardinal-Deacon |
| Consistory of 1539.12.19 (at the time of creation) (12) |
| 1. | Archbishop Federico Fregóso (59), Apostolic Administrator of Gubbio (Italy) and Metropolitan Archbishop emeritus of Salerno (Italy) | Cardinal-Priest |
| 2. | Archbishop Pierre de La Baume, O. Cist. (62), Abbot nullius of Saint-Claude (France), Bishop of Genève (Switzerland) and Coadjutor Archbishop of Besançon (France) | Cardinal-Priest |
| 3. | Bishop Antoine Sanguin de Meudon (46), Bishop of Orléans (France) | Cardinal-Priest |
| 4. | Bishop Uberto Gàmbara (50), Bishop of Tortona (Italy) | Cardinal-Priest |
| 5. | Bishop Pierpaolo Parisio (66), Bishop of Nusco (Italy) | Cardinal-Priest |
| 6. | Bishop-elect Marcello Cervini (38), Bishop of Nicastro (Italy) | Cardinal-Priest |
| 7. |  Fr. Bartolomeo Guidiccioni (69) | Cardinal-Priest |
| 8. | Bishop Ascanio Parisani, Bishop of Rimini (Italy) | Cardinal-Priest |
| 9. | Fr. Dionisio Neagrus Laurerio, O.S.M. (42), Prior General of Order of Friar Servants of Mary (Servites) | Cardinal-Priest |
| 10. | Mr. Enrique de Borja y Aragón (20) | Cardinal-Deacon |
| 11. | Mr. Giacomo Savelli (16) | Cardinal-Deacon |
| (12) | Bishop Miguel da Silva (59), Bishop of Viseu (Portugal) | Cardinal-Priest |
| Consistory of 1542.06.02 (at the time of creation) (8) |
| 1. | Bishop Giovanni Girolamo Morone (33), Bishop of Modena (Italy) | Cardinal-Priest |
| 2. | Bishop Marcello Crescenzi (42), Bishop of Marsi (Italy) | Cardinal-Priest |
| 3. | Bishop Giovanni Vincenzo Acquaviva d’Aragona (52), Bishop of Rapolla (Italy) and Bishop of Melfi (Italy) | Cardinal-Priest |
| 4. | Bishop Pomponio Cecci, Bishop of Sutri (Italy), Bishop of Nepi (Italy) and Vicar General for the Vicariate of Rome of Roma (Italy) | Cardinal-Priest |
| 5. | Bishop Roberto Pucci (77), Bishop of Pistoia (Italy) | Cardinal-Priest |
| 6. | Fr. Tommaso Badia, O.P. (58), Master of the Sacred Palace of Prefecture of the Holy Apostolic Palaces | Cardinal-Priest |
| 7. | Fr. Gregorio Cortese, O.S.B. Cas. (59) | Cardinal-Priest |
| (8) | Bishop-elect Cristoforo Madruzzo (29), Bishop of Trento (Italy) | Cardinal-Priest |
| Consistory of 1544.12.19 (at the time of creation) (13) |
| 1. | Archbishop Gaspar de Ávalos de la Cueva (59), Metropolitan Archbishop of Santiago de Compostela (Spain) | Cardinal-Priest |
| 2. | Bishop Francisco Mendoza de Bobadilla (36), Bishop of Coria (Spain) | Cardinal-Priest |
| 3. | Fr. Bartolomé de la Cueva y Toledo (45) | Cardinal-Priest |
| 4. | Bishop Georges d’Armagnac (43), Bishop of Rodez (France) and Bishop of Vabres (France) | Cardinal-Priest |
| 5. | Bishop Jacques d’Annebaut (44), Bishop of Lisieux (France) | Cardinal-Priest |
| 6. |  Bishop Otto Truchsess von Waldburg (30), Bishop of Augsburg (Germany) | Cardinal-Priest |
| 7. |  Fr. Andrea Cornaro (32), Bishop of Brescia (Italy) | Cardinal-Deacon |
| 8. | Archbishop Francesco Sfondrati (51), Metropolitan Archbishop of Amalfi (Italy) | Cardinal-Priest |
| 9. | Bishop Federico Cesi (44), Bishop of Todi (Italy) | Cardinal-Priest |
| 10. | Bishop Durante Duranti (37), Bishop of Cassano all’Jonio (Italy) | Cardinal-Priest |
| 11. | Bishop Niccolò Ardinghelli (41), Bishop of Fossombrone (Italy) | Cardinal-Priest |
| 12. | Bishop-elect Girolamo Recanati Capodiferro (42), Bishop of Saint-Jean-de-Maurienne (France) | Cardinal-Deacon |
| 13. | Bishop-elect Tiberio Crispo (46), Bishop of Sessa Aurunca (Italy) | Cardinal-Deacon |
| Consistory of 1545.12.16 (at the time of creation) (4) |
| 1. | Bishop Pedro Pacheco de Villena (57), Bishop of Jaén (Spain) | Cardinal-Priest |
| 2. | Archbishop Georges d’Amboise (57), Metropolitan Archbishop of Rouen (France) | Cardinal-Priest |
| 3. |  Archbishop Henrique de Portugal (33), Metropolitan Archbishop of Évora (Portugal) | Cardinal-Priest |
| 4. | Mr. Ranuccio Farnese, S.M.O.M. (15), Apostolic Administrator of Napoli (Italy) | Cardinal-Deacon |
| Consistory of 1547.07.27 (at the time of creation) (2) |
| 1. | Archbishop Charles de Guise de Lorraine (23), Metropolitan Archbishop of Reims (France) | Cardinal-Priest |
| (2) | Mr. Giulio della Rovere (14) | Cardinal-Deacon |
| Consistory of 1548.01.09 (at the time of creation) (1) |
| 1. | Bishop-elect Charles de Bourbon-Vendôme (24), Bishop of Saintes (France) | Cardinal-Deacon |
| Consistory of 1549.04.08 (at the time of creation) (4) |
| 1. | Archbishop Girolamo Verallo (52), Archbishop of Rossano (Italy) | Cardinal-Priest |
| 2. | Archbishop Giovanni Angelo Medici (49), Metropolitan Archbishop of Ragusa (Croatia) | Cardinal-Priest |
| 3. | Bishop Filiberto Ferrero (49), Bishop of Ivrea (Italy) | Cardinal-Priest |
| 4. | Bishop Bernardino Maffei (35), Bishop of Massa Marittima e Populonia (Italy) | Cardinal-Priest |
(71)
