| Consistory of 1492.08.31 (at the time of creation) (1) |
| 1. |   Archbishop Juan de Borja Lanzol de Romaní (46), Metropolitan Archbishop of Monreale (Italy) | Cardinal-Priest |
| Consistory of 1493.09.20 (at the time of creation) (12) |
| 1. |   Bishop Jean Bilhères de Lagraulas, O.S.B. Clun. (59), Bishop of Lombez (France) | Cardinal-Priest |
| 2. | Bishop Giovanni Antonio Sangiorgio (54), Bishop of Alessandria (Italy) | Cardinal-Priest |
| 3. |  Bishop Bernardino López de Carvajal (36), Bishop of Cartagena (Spain) | Cardinal-Priest |
| 4. |  Msgr. César Borgia (17), Metropolitan Archbishop of Valencia (Spain) and Apostolic Administrator of Nantes (France) | Cardinal-Deacon |
| 5. | Mr. Giuliano Cesarini (27) | Cardinal-Deacon |
| 6. | Mr. Domenico Grimani (32) | Cardinal-Deacon |
| 7. | Mr. Alessandro Farnese (25) | Cardinal-Deacon |
| 8. | Mr. Bernardino Lunati (41) | Cardinal-Deacon |
| 9. | Bishop Raymund Pérault, O.E.S.A. (58), Bishop of Gurk (Austria) | Cardinal-Deacon |
| 10. |  Archbishop John Morton (73), Metropolitan Archbishop of Canterbury (England) | Cardinal-Priest |
| 11. |  Bishop-elect Fryderyk Jagiellończyk (25), Bishop of Kraków (Poland) | Cardinal-Deacon |
| 12. |  Bishop Ippolito d’Este (Hippolit Estei) (14), Apostolic Administrator of Esztergom (Hungary) | Cardinal-Deacon |
| Consistory of 1494.05 (at the time of creation) (1) |
| (1) | Mr. Luigi d’Aragona (19) | Cardinal-Deacon |
| Consistory of 1495.01.16 (at the time of creation) (1) |
| 1. | Bishop Guillaume Briçonnet (49), Bishop of Saint-Malo (France) | Cardinal-Priest |
| Consistory of 1495.01.21 (at the time of creation) (1) |
| 1. | Bishop Philippe de Luxembourg (49), Bishop of Le Mans (France) | Cardinal-Priest |
| Consistory of 1496.02.19 (at the time of creation) (4) |
| 1. | Bishop Juan López (41), Bishop of Perugia (Italy) and Datary of His Holiness of Apostolic Dataria | Cardinal-Priest |
| 2. | Bishop Bartolomé Martí (66), Bishop of Segorbe–Albarracín (Spain) | Cardinal-Priest |
| 3. |  Bishop Juan de Castro (64), Bishop of Agrigento (Italy) | Cardinal-Priest |
| 4. | Bishop Juan de Borja Llançol de Romaní (26), Metropolitan Archbishop of Capua (Italy) and Bishop of Melfi (Italy) | Cardinal-Deacon |
| Consistory of 1498.09.17 (at the time of creation) (1) |
| 1. | Archbishop Georges d’Amboise (38), Metropolitan Archbishop of Rouen (France) | Cardinal-Priest |
| Consistory of 1500.03.20 (at the time of creation) (3) |
| (1) | Archbishop Diego Hurtado de Mendoza (56), Metropolitan Archbishop of Sevilla (Spain) | Cardinal-Priest |
| (2) | Bishop Amanieu d’Albret (22), Apostolic Administrator of Saint-Bertrand-de-Comminges (France) | Cardinal-Deacon |
| (3) | Mr. Pedro Luis de Borja Llançol de Romaní, O.E.S.S.H. (28) | Cardinal-Deacon |
| Consistory of 1500.09.28 (at the time of creation) (10) |
| (1) | Archbishop Jaime Serra i Cau (73), Metropolitan Archbishop of Oristano (Italy) and Vicar General for the Vicariate of Rome of Roma (Italy) | Cardinal-Priest |
| (2) | Archbishop Pietro Isvalies, Metropolitan Archbishop of Reggio Calabria (Italy) | Cardinal-Priest |
| (3) | Archbishop Francisco de Borja (59), Metropolitan Archbishop of Cosenza (Italy) and Apostolic Administrator of Teano (Italy) | Cardinal-Priest |
| (4) | Archbishop Juan de Vera (46), Metropolitan Archbishop of Salerno (Italy) | Cardinal-Priest |
| (5) | Bishop Ludovico Podocathor (71), Bishop of Capaccio (Italy) | Cardinal-Priest |
| (6) | Bishop Antonio Trivulzio, C.R.S.Ant. (43), Bishop of Como (Italy) | Cardinal-Priest |
| (7) | Bishop Giovanni Battista Ferrari (50), Bishop of Modena (Italy) and Datary of His Holiness of Apostolic Dataria | Cardinal-Priest |
| (8) |  Archbishop Tamás Bakócz (58), Metropolitan Archbishop of Esztergom (Hungary) | Cardinal-Priest |
| (9) |  Bishop Marco Cornaro (18) | Cardinal-Deacon |
| (10) | Bishop Gianstefano Ferrero (26), Bishop of Vercelli (Italy) | Cardinal-Priest |
| Consistory of 1503.05.31 (at the time of creation) (9) |
| (1) | Archbishop Juan Castellar y de Borja (62), Metropolitan Archbishop of Trani (Italy) | Cardinal-Priest |
| (2) | Archbishop Francisco de Remolins (41), Metropolitan Archbishop of Sorrento (Italy) | Cardinal-Priest |
| (3) | Bishop Francesco Soderini (49), Bishop of Volterra (Italy) | Cardinal-Priest |
| (4) | Bishop Melchior von Meckau (63), Bishop of Brixen (Italy) | Cardinal-Priest |
| (5) | Bishop Niccolò Fieschi (47), Bishop of Fréjus (France) | Cardinal-Deacon |
| (6) | Bishop Francisco Desprats (49), Bishop of León (Spain) | Cardinal-Priest |
| (7) | Bishop Adriano di Castello (45), Bishop of Hereford (England) | Cardinal-Priest |
| (8) |  Fr. Jaime de Casanova (68) | Cardinal-Priest |
| (9) | Bishop Francisco Lloris y de Borja (Williovis) (33), Bishop of Elne (France) and Apostolic Administrator of Die (France) | Cardinal-Deacon |
(43)
