| Rector Magnificus: |   Fr. Mauro Mantovani, S.D.B. (58) (2015 – 2021) |
| Rector Magnificus: | Fr. Carlo Nanni, S.D.B. (2009 – 2015.07.15) |
| Rector Magnificus: |  Fr. Mario Toso, S.D.B. (74) (later Bishop) (2003 – 2009.10.22) |
| Rector Magnificus: | Fr. Michele Pellerey, S.D.B. (1997 – 2003) |
| Rector Magnificus: |  Fr. Raffaele Farina, S.D.B. (90) (later Cardinal) (1991 – 1997) |
| Rector Magnificus: | Fr. Tarcisio Bertone, S.D.B. (89) (later Cardinal) (1989.06.01 – 1991.06.04) |
| Rector Magnificus: | Fr. Roberto Giannatelli, S.D.B. (1983 – 1989) |
| Rector Magnificus: | Fr. Raffaele Farina, S.D.B. (90) (later Cardinal) (1977 – 1983) |
| Rector Magnificus: | Fr. Pietro Braido, S.D.B. (1974 – 1977) |
| Rector Magnificus: |  Fr. Antonio María Javierre Ortas, S.D.B. (later Cardinal) (1971 – 1974) |
| Rector Magnificus: | Fr. Luigi Calonghi, S.D.B. (1968 – 1971) |
| Rector Magnificus: | Fr. Gino Corallo, S.D.B. (1966 – 1968) |
| Rector Magnificus: |  Fr. Alfons Maria Stickler, S.D.B. (later Cardinal) (1958 – 1966) |
| Rector Magnificus: | Fr. Eugenio Valentini, S.D.B. (1952 – 1958) |
| Rector Magnificus: | Fr. Andrea Gennaro, S.D.B. (1940 – 1952) |
| Pro-Rector: | Fr. Angelo Amato, S.D.B. (86) (later Cardinal) (1991.10.01 – 1991.12.02) |
| Grand Chancellor: |  Cardinal Ángel Fernández Artime, S.D.B. (64) (2014.03.25 – 2024.08.16) |
| Grand Chancellor: |   Fr. Pascual Chávez Villanueva, S.D.B. (76) (2002.04.03 – 2014.03.25) |
