| President: |  Mr. Ernst von Freyberg (2013.02.15 – 2014.07.09) |
| President: |  Mr. Ettore Gotti Tedeschi (2009.09.23 – 2012.05.24) |
| President: | Mr. Angelo Caloia (1989 – 2009.09.23) |
| President: |  Archbishop Paul Casimir Marcinkus (1971 – 1989) |
| President: | Mr. Massimo Spada (1954 – 1971) |
| President: | Mr. Bernardino Nogara (1942.06.27 – 1954) |
| President ad interim: | Mr. Ronaldo Hermann Schmitz (86) (2012.05.25 – 2013.02.15) |
| Vice-President: | Mr. Ronaldo Hermann Schmitz (86) (2009 – 2012.05.24) |
| Vice-President: | Mr. Virgil C. Dechant (1998 – 2009) |
| Vice-President: | Mr. Philippe De Weck (1989 – 1997) |
| Director General: | Mr. Rolando Marranci (2013.11.30 – 2015.11.24) |
| Director General: | Mr. Paolo Cipriani (2007.10.01 – 2013.07.01) |
| Director General: | Mr. Lelio Scaletti (1995 – 2007.10.01) |
| Director General: | Mr. Andrea Gibellini (1992 – 1995) |
| Director General: | Mr. Giovanni Bodio (1991 – 1992) |
| Director General ad interim: | Mr. Ernst von Freyberg (2013.07.01 – 2013.11.30) |
| Deputy Director General: | Mr. Giulio Mattietti (2015.11.24 – 2017.11.27) |
| Deputy Director General: | Mr. Gianfranco Mammì (68) (2015.03.06 – 2015.11.24) |
| Deputy Director General: | Dr. Massimo Tulli (2007 – 2013.07.01) |
| Deputy Director General: | Mr. Paolo Cipriani (2006 – 2007.10.01) |
| Deputy Director General: | Mr. Dario Sabbioni (2003 – 2006) |
| Deputy Director General: | Dr. Mario Trippanera (2000 – 2001) |
| Deputy Director General: | Mr. Pier Giorgio Tartaglia (1998 – 2000) |
| Deputy Director General: | Mr. Lelio Scaletti (1992 – 1995) |
| Deputy Director General ad interim: | Mr. Rolando Marranci (2013.07.01 – 2013.11.30) |
| Assistant Deputy Director General: | Mr. Alessandro Lombardi (1998 – 2003) |
| Secretary of the Board: |   Msgr. Alfred Xuereb (66) (later Archbishop) (2014.07.09 – 2018.02.26) |
| Prelate: | Msgr. Piero Pioppo (64) (later Archbishop) (2006.07.07 – 2010.01.25) |
| Secretary General of Administrative Office: | Msgr. Donato De Bonis (later Bishop) (1988 – 1989) |
| Secretary General of Administrative Office: | Msgr. Carmine Vincenti (1944 – 1954) |
| Secretary General of Administrative Office: | Msgr. Alberto Di Jorio (later Cardinal) (1942.06.27 – 1947.04.01) |
| Secretary of Administrative Office: | Msgr. Donato De Bonis (later Bishop) (1970 – 1988) |
| Secretary of Administrative Office: | Archbishop Paul Casimir Marcinkus (1969 – 1970) |
| Secretary of Administrative Office: | Msgr. Enrico Arato (1955 – 1968) |
(x 7)
Mr. Jean-Baptiste Douville de Franssu (61)
Msgr. Battista Mario Salvatore Ricca (69)