 | 1949 | 1950 | 1951 |  |
Date | Country | Change |
| 1950 |  Lebanon | Titular Episcopal See of Arca in Phœnicia (Maronite Rite) was restored |
| 1950 |  Turkiye | Titular Episcopal See of Ægeæ was restored |
| 1950.01.14 |  USA | Diocese of Worcester was established (from Diocese of Springfield in Massachusetts and became suffragan of Boston) |
| 1950.01.19 |  Italy | Diocese of Cuneo exchanged territory with Diocese of Mondovì |
| 1950.01.19 | Italy | Diocese of Mondovì exchanged territory with Diocese of Cuneo |
| 1950.01.24 | Italy | Diocese of Penne e Pescara lost territory to Diocese of Teramo |
| 1950.02.02 |  Liberia | Apostolic Prefecture of Cape Palmas was established (from Apostolic Vicariate of Liberia) |
| 1950.02.02 | Liberia | Apostolic Vicariate of Liberia was renamed as Apostolic Vicariate of Monrovia (lost territory to establish Apostolic Prefecture of Cape Palmas) |
| 1950.02.07 |  Indonesia | Apostolic Vicariate of Batavia was renamed as Apostolic Vicariate of Djakarta |
| 1950.03.10 |  Colombia | Apostolic Prefecture of Sinú–San Jorge was promoted as Apostolic Vicariate of San Jorge |
| 1950.03.10 |  Namibia | Apostolic Vicariate of Windhoek lost territory to Apostolic Vicariate of Livingstone |
| 1950.03.10 |  Zambia | Apostolic Prefecture of Victoria Falls was promoted as Apostolic Vicariate of Livingstone (gained territory from Apostolic Vicariate of Windhoek) |
| 1950.03.19 | Italy | Diocese of Terracina exchanged territory with Diocese of Velletri |
| 1950.03.19 | Italy | Diocese of Velletri exchanged territory with Diocese of Terracina |
| 1950.03.28 |  Philippines | Diocese of Lucena was established (from Diocese of Lipa and became suffragan of Manila) |
| 1950.04.18 |  Cameroon | Apostolic Vicariate of Buéa was promoted as Diocese of Buéa (became suffragan of Onitsha) |
| 1950.04.18 |  China | Apostolic Prefecture of Hongtong 洪洞 was promoted as Diocese of Hongtong 洪洞 (became suffragan of Taiyuan 太原) |
| 1950.04.18 | Colombia | Apostolic Prefecture of Río Magdalena was promoted as Apostolic Vicariate of Barrancabermeja |
| 1950.04.18 |  Ghana | Apostolic Vicariate of Accra was promoted as Diocese of Accra (became suffragan of Cape Coast) |
| 1950.04.18 | Ghana | Apostolic Vicariate of Gold Coast was promoted as Metropolitan Archdiocese of Cape Coast (with suffragan sees Accra, Keta, Kumasi and Tamale) |
| 1950.04.18 | Ghana | Apostolic Vicariate of Lower Volta was promoted as Diocese of Keta (became suffragan of Cape Coast) |
| 1950.04.18 | Ghana | Apostolic Vicariate of Kumasi was promoted as Diocese of Kumasi (became suffragan of Cape Coast) |
| 1950.04.18 | Ghana | Apostolic Vicariate of Navrongo was suppressed (to establish Diocese of Tamale) |
| 1950.04.18 | Ghana | Diocese of Tamale was established (from the suppressed Apostolic Vicariate of Navrongo and became suffragan of Cape Coast) |
| 1950.04.18 |  Nigeria | Apostolic Vicariate of Asaba-Benin was promoted as Diocese of Benin City (became suffragan of Lagos) |
| 1950.04.18 | Nigeria | Apostolic Vicariate of Calabar was promoted as Diocese of Calabar (became suffragan of Onitsha) |
| 1950.04.18 | Nigeria | Apostolic Vicariate of Lagos was promoted as Metropolitan Archdiocese of Lagos (with suffragan sees Benin City and Ondo) |
| 1950.04.18 | Nigeria | Apostolic Vicariate of Ondo-Ilorin was promoted as Diocese of Ondo (became suffragan of Lagos) |
| 1950.04.18 | Nigeria | Apostolic Vicariate of Onitsha was promoted as Metropolitan Archdiocese of Onitsha (with suffragan sees Buéa, Calabar and Owerri) |
| 1950.04.18 | Nigeria | Apostolic Prefecture of Benue was renamed as Apostolic Prefecture of Oturkpo |
| 1950.04.18 | Nigeria | Apostolic Vicariate of Owerri was promoted as Diocese of Owerri (became suffragan of Onitsha) |
| 1950.04.18 |  Sierra Leone | Apostolic Vicariate of Sierra Leone was promoted as Diocese of Freetown and Bo (without ecclesiastical province) |
| 1950.04.18 |  Tanzania | Apostolic Prefecture of Tanga was established (from Apostolic Vicariate of Kilima-Njaro) |
| 1950.04.25 | Philippines | Territorial Prelature of Infanta was established (from Diocese of Lipa and became suffragan of Manila) |
| 1950.05.06 |  Mexico | Mission sui juris of Tarahumara was established (from Diocese of Chihuahua and became suffragan of Durango) |
| 1950.05.24 |  Congo-Kinshasa | Apostolic Vicariate of Coquilhatville lost territory to Apostolic Vicariate of Léopoldville |
| 1950.05.24 | Congo-Kinshasa | Apostolic Vicariate of Kisantu lost territory to Apostolic Vicariate of Léopoldville |
| 1950.05.24 | Congo-Kinshasa | Apostolic Vicariate of Kwango lost territory to Apostolic Vicariate of Léopoldville |
| 1950.05.26 |  Myanmar | Apostolic Prefecture of Kengtung was promoted as Apostolic Vicariate of Kengtung |
| 1950.05.27 |  Brazil | Diocese of Cafelândia was renamed as Diocese of Lins |
| 1950.06.04 | Mexico | Diocese of Toluca was established (from Metropolitan Archdiocese of México and became suffragan of México) |
| 1950.06.24 | China | Apostolic Prefecture of Pingliang 平涼 was promoted as Diocese of Pingliang 平涼 (became suffragan of Lanzhou 蘭州) |
| 1950.06.24 | Indonesia | Apostolic Vicariate of Merauke was established (from Apostolic Vicariate of Amboina) |
| 1950.06.24 | Tanzania | Apostolic Vicariate of Maswa was established (from Apostolic Vicariate of Musoma-Maswa) |
| 1950.06.24 | Tanzania | Apostolic Vicariate of Musoma-Maswa was demoted as Apostolic Prefecture of Musoma (lost territory to establish Apostolic Vicariate of Maswa) |
| 1950.06.24 |  Zimbabwe | Apostolic Prefecture of Fort Victoria was promoted as Apostolic Vicariate of Fort Victoria |
| 1950.07.10 | Indonesia | Apostolic Prefecture of Denpasar was established (from Apostolic Vicariate of Lesser Sunda Islands) |
| 1950.07.11 | Italy | Diocese of Noto lost territory to Metropolitan Archdiocese of Siracusa |
| 1950.07.11 | Italy | Diocese of Ragusa was established (from Metropolitan Archdiocese of Siracusa and Diocese of Noto and became suffragan of Siracusa) |
| 1950.07.12 |  North Korea | Apostolic Vicariate of Kanko was renamed as Apostolic Vicariate of Hamhung 함흥 |
| 1950.07.12 | North Korea | Apostolic Vicariate of Heijo was renamed as Apostolic Vicariate of Pyong-Yang 평양 |
| 1950.07.12 | North Korea | Territorial Abbacy of Tŏkugen was renamed as Territorial Abbacy of Tŏkwon 덕원 |
| 1950.07.12 |  South Korea | Apostolic Prefecture of Kwoszu was renamed as Apostolic Prefecture of Gwangju 광주 |
| 1950.07.12 | South Korea | Apostolic Prefecture of Zenshu was renamed as Apostolic Prefecture of Jeonju 전주 |
| 1950.07.12 | South Korea, North Korea | Apostolic Vicariate of Seoul 서울 was renamed as Apostolic Vicariate of Seul 서울 |
| 1950.07.14 | Nigeria | Apostolic Prefecture of Yola was established (from Diocese of Buéa, Apostolic Prefecture of Jos and Apostolic Prefecture of Oturkpo) |
| 1950.07.14 |  Paraguay | Apostolic Prefecture of Pilcomayo was promoted as Apostolic Vicariate of Pilcomayo |
| 1950.07.14 | Zambia | Apostolic Prefecture of Lusaka was promoted as Apostolic Vicariate of Lusaka |
| 1950.07.15 |  Bangladesh | Diocese of Dacca was promoted as Metropolitan Archdiocese of Dacca (with suffragan sees Chittagong and Dinajpur) |
| 1950.07.15 |  Pakistan | Diocese of Karachi was promoted as Metropolitan Archdiocese of Karachi (with suffragan sees Lahore, Multan and Rawalpindi) |
| 1950.07.16 | South Korea, North Korea | Apostolic Prefecture of Shunsen was renamed as Apostolic Prefecture of Chunchon 춘천 |
| 1950.07.25 |  India | Diocese of Palai (Syro-Malabar Rite) was established (from Diocese of Changanacherry and became suffragan of Ernakulam) |
| 1950.08.05 |  Spain | Military Vicariate of Spain was restored |
| 1950.08.10 |  Taiwan | Apostolic Prefecture of Taichung 臺中 was established (from Apostolic Prefecture of Kaohsung 高雄) |
| 1950.08.11 | Brazil | Apostolic Prefecture of Alto Solimões was promoted as Territorial Prelature of Alto Solimões (became suffragan of Belém do Pará) |
| 1950.08.11 | Brazil | Apostolic Prefecture of Tefé was promoted as Territorial Prelature of Tefé (became suffragan of Belém do Pará) |
| 1950.08.11 | Philippines | Territorial Prelature of Cotabato and Sulu was established (from Diocese of Zamboanga and became suffragan of Manila) |
| 1950.09.15 | Italy | Diocese of Mazara del Vallo exchanged territory with Diocese of Trapani |
| 1950.09.15 | Italy | Diocese of Trapani exchanged territory with Diocese of Mazara del Vallo |
| 1950.10.21 | India | Apostolic Prefecture of Jubbulpore was renamed as Apostolic Prefecture of Jabalpur |
| 1950.10.21 | India | Diocese of Madura was renamed as Diocese of Madurai |
| 1950.10.21 | India | Diocese of Trichinopoly was renamed as Diocese of Tiruchirapalli |
| 1950.10.21 | India | Diocese of Bezwada was renamed as Diocese of Vijayawada |
| 1950.10.21 | India | Diocese of Vizagapatam was renamed as Diocese of Visakhapatnam |
| 1950.11.06 | Brazil | Military Vicariate of Brazil was established |
| 1950.11.30 | Philippines | Territorial Prelature of Batanes and the Babuyan Islands was established (from Diocese of Tuguegarao and became suffragan of Manila) |
| 1950.12.01 |  Uganda | Apostolic Vicariate of Equatorial Nile was renamed as Apostolic Vicariate of Gulu |
| 1950.12.08 | Philippines | Military Vicariate of Philippines was established |
| 1950.12.12 | Turkiye | Titular Episcopal See of Sion was promoted as Titular Archiepiscopal See of Sion |
| 1950.12.21 |  Congo-Brazzaville | Apostolic Vicariate of Fort-Rousset was established (from Apostolic Vicariate of Brazzaville) |
| 1950.12.21 |  Laos | Apostolic Prefecture of Thakhek was established (from Apostolic Vicariate of Laos) |
| 1950.12.21 |  Thailand | Apostolic Vicariate of Laos was renamed as Apostolic Vicariate of Thare (lost territory to establish Apostolic Prefecture of Thakhek) |
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