 | 1948 | 1949 | 1950 |  |
Date | Country | Change |
| 1949 |  Egypt | Titular Episcopal See of Hermopolis maior was suppressed |
| 1949 |  Spain | Apostolic Administration of Ibiza was promoted as Diocese of Ibiza (became suffragan of Valencia) |
| 1949.01.13 |  Madagascar | Apostolic Prefecture of Tsiroanomandidy was established (from Apostolic Vicariate of Miarinarivo) |
| 1949.01.13 |  Namibia | Apostolic Vicariate of Great Namaqualand was renamed as Apostolic Vicariate of Keetmanshoop |
| 1949.01.13 |  Zambia | Apostolic Prefecture of Ndola was promoted as Apostolic Vicariate of Ndola |
| 1949.01.20 |  Congo-Brazzaville | Apostolic Vicariate of Loango was renamed as Apostolic Vicariate of Pointe-Noire |
| 1949.02.01 |  Brazil | Territorial Prelature of Macapá was established (from Territorial Prelature of Santarém and became suffragan of Belém do Pará) |
| 1949.03.03 |  Cameroon | Apostolic Vicariate of Doumé was established (from Apostolic Vicariate of Yaoundé) |
| 1949.03.03 |  China | Diocese of Yongjia 永嘉 was established (from Diocese of Ningbo 寧波 and became suffragan of Hangzhou 杭州) |
| 1949.03.03 |  Nigeria | Apostolic Prefecture of Oyo was established (from Apostolic Vicariate of Lagos) |
| 1949.03.03 |  South Sudan | Apostolic Prefecture of Mupoi was established (from Apostolic Vicariate of Bahr el-Ghazal and Apostolic Prefecture of Bahr el-Gebel) |
| 1949.03.06 |  Honduras | Territorial Prelature of Inmaculada Concepción de la B.V.M. en Olancho was established (from Metropolitan Archdiocese of Tegucigalpa and became suffragan of Tegucigalpa) |
| 1949.03.10 |  Congo-Kinshasa | Apostolic Vicariate of Kasaï Supérieur was renamed as Apostolic Vicariate of Luluabourg |
| 1949.03.10 | Congo-Kinshasa | Apostolic Vicariate of Stanley Falls was renamed as Apostolic Vicariate of Stanleyville (lost territory to establish Apostolic Vicariate of Wamba) |
| 1949.03.10 | Congo-Kinshasa | Apostolic Vicariate of Wamba was established (from Apostolic Vicariate of Stanley Falls) |
| 1949.03.10 |  India | Mission sui juris of Bellary was promoted as Diocese of Bellary |
| 1949.03.10 |  Indonesia | Apostolic Prefecture of Bandjarmasin was promoted as Apostolic Vicariate of Bandjarmasin |
| 1949.03.10 |  Peru | Apostolic Vicariate of Urubamba y Madre de Dios was renamed as Apostolic Vicariate of Puerto Maldonado |
| 1949.04.21 | China | Apostolic Prefecture of Chifeng 赤峰 was promoted as Diocese of Chifeng 赤峰 (became suffragan of Shenyang 瀋陽) |
| 1949.05.05 | India | Mission sui juris of Ahmedabad was promoted as Diocese of Ahmedabad (became suffragan of Bombay) |
| 1949.05.12 |  Guinea | Apostolic Vicariate of French Guinea was renamed as Apostolic Vicariate of Conakry (lost territory to establish Apostolic Prefecture of Kankan) |
| 1949.05.12 | Guinea | Apostolic Prefecture of Kankan was established (from Apostolic Vicariate of French Guinea) |
| 1949.05.12 | Indonesia | Apostolic Vicariate of Dutch New Guinea was renamed as Apostolic Vicariate of Amboina (lost territory to establish Apostolic Prefecture of Hollandia) |
| 1949.05.12 | Indonesia | Apostolic Prefecture of Hollandia was established (from Apostolic Vicariate of Dutch New Guinea) |
| 1949.05.14 | Brazil | Diocese of Campina Grande was established (from Metropolitan Archdiocese of Paraíba and became suffragan of Paraíba) |
| 1949.05.14 |  Italy | Diocese of Tricarico lost territory to Diocese of Anglona–Tursi |
| 1949.06.09 | China | Apostolic Prefecture of Haizhou 海州 was established (from Diocese of Shanghai 上海) |
| 1949.06.09 | China | Diocese of Suzhou 蘇州 was established (from Diocese of Shanghai 上海 and became suffragan of Nanjing 南京) |
| 1949.06.09 | China | Apostolic Prefecture of Yangzhou 揚州 was established (from Diocese of Shanghai 上海) |
| 1949.06.09 |  Colombia | Apostolic Prefecture of Mitú was established (from Apostolic Vicariate of Los Llanos de San Martín) |
| 1949.06.09 | Colombia | Apostolic Vicariate of Los Llanos de San Martín was renamed as Apostolic Vicariate of Villavicencio (lost territory to establish Apostolic Prefecture of Mitú) |
| 1949.07.01 | Italy | Metropolitan Archdiocese of Chieti lost territory to Diocese of Penne e Pescara |
| 1949.07.01 | Italy | Diocese of Penne was renamed as Diocese of Penne e Pescara (gained territory from Metropolitan Archdiocese of Chieti and lost territory to Diocese of Teramo) |
| 1949.07.14 |  Burundi | Apostolic Vicariate of Urundi was renamed as Apostolic Vicariate of Kitega (lost territory to establish Apostolic Vicariate of Ngozi) |
| 1949.07.14 | Burundi | Apostolic Vicariate of Ngozi was established (from Apostolic Vicariate of Urundi) |
| 1949.07.14 | China | Diocese of Yingkou 營口 was established (from Metropolitan Archdiocese of Shenyang 瀋陽 and became suffragan of Shenyang 瀋陽) |
| 1949.07.14 | South Sudan | Apostolic Prefecture of Kodok was renamed as Apostolic Prefecture of Malakal |
| 1949.07.14 |  Tanzania | Apostolic Prefecture of Tukuyu was promoted as Apostolic Vicariate of Mbeya |
| 1949.07.16 |  Paraguay | Diocese of Concepción y Chaco was renamed as Diocese of Concepción |
| 1949.10.13 | Colombia | Military Vicariate of Colombia was established |
| 1949.11.02 | Spain | Diocese of Albacete was established (from Diocese of Cartagena, Diocese of Cuenca and Diocese of Orihuela and became suffragan of Valencia) |
| 1949.11.02 | Spain | Diocese of Bilbao was established (from Diocese of Santander and Diocese of Vitoria and became suffragan of Burgos) |
| 1949.11.02 | Spain | Diocese of Calahorra y La Calzada lost territory to Diocese of Vitoria |
| 1949.11.02 | Spain | Diocese of San Sebastián was established (from Diocese of Vitoria and became suffragan of Burgos) |
| 1949.12.16 |  Sudan | Apostolic Vicariate of Khartoum lost territory to Apostolic Vicariate of Egypt |
| 1949.12.17 |  Philippines | Territorial Prelature of Davao was established (from Diocese of Zamboanga and became suffragan of Cebu) |
| 1949.12.25 |  Bolivia | Territorial Prelature of Corocoro was established (from Metropolitan Archdiocese of La Paz and became suffragan of La Paz) |
| 1949.12.25 | Indonesia | Military Vicariate of Indonesia was established |
| 1949.12.30 |  Taiwan | Apostolic Prefecture of Formosa Island 台灣 was renamed as Apostolic Prefecture of Kaohsung 高雄 (lost territory to establish Apostolic Prefecture of Taipei 臺北) |
| 1949.12.30 | Taiwan | Apostolic Prefecture of Taipei 臺北 was established (from Apostolic Prefecture of Formosa Island 台灣) |
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