| Date | Country | Change |
| 1860 | Titular Archiepiscopal See of Perat-Maishan (Chaldean Rite) was restored | |
| 1860.01.24 | Apostolic Vicariate of Southern Szechwan 四川南境 was established (from Apostolic Vicariate of Northwestern Szechwan 四川西北) | |
| 1860.02.26 | Apostolic Prefecture of Zanguebar was established (from Diocese of Saint-Denis-de-La Réunion) | |
| 1860.04.21 | Archdiocese of Barletta was restored (from Metropolitan Archdiocese of Trani and became suffragan of Trani) | |
| 1860.04.21 | Titular Metropolitan See of Nazareth was restored (no longer united) | |
| 1860.05.08 | Diocese of Chatham was established (from Diocese of Saint John in America and became suffragan of Halifax) | |
| 1860.06.14 | Diocese of Bytown was renamed as Diocese of Ottawa | |
| 1860.06.14 | Diocese of Fréjus lost territory to Diocese of Nice | |
| 1860.06.14 | Diocese of Nice lost territory to Diocese of Cuneo | |
| 1860.06.14 | Diocese of Ventimiglia lost territory to Diocese of Cuneo | |
| 1860.08.28 | Apostolic Vicariate of Dahomey was established (from Apostolic Vicariate of Deux Guinées et Sénégambie) | |
| 1860.09.27 | Apostolic Vicariate of Marysville was established (from Metropolitan Archdiocese of San Francisco) | |
| 1860.11.16 | Apostolic Vicariate of Northern District of Scotland lost territory to Apostolic Prefecture of North Pole |
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