 | 2000 | 2001 | 2002 |  |
Date | Country | Change |
| 2001 |  Brazil | Diocese of Uruguaiana lost territory to Diocese of Santo Ângelo |
| 2001 |  Jordan,  Israel,  Palestine | Territory Dependent on the Patriarch of Amman and Jerusalem (Armenian Rite) was promoted as Patriarchal Exarchate of Jerusalem and Amman |
| 2001.01.11 |  North Macedonia | Apostolic Exarchate of Macedonia (Macedonian Rite) was established (from Diocese of Križevci) |
| 2001.01.23 |  Colombia | Apostolic Prefecture of Guapi was promoted as Apostolic Vicariate of Guapi |
| 2001.01.30 |  Italy | Archdiocese of Catanzaro–Squillace was promoted as Metropolitan Archdiocese of Catanzaro–Squillace (with suffragan sees Crotone–Santa Severina and Lamezia Terme) |
| 2001.01.30 | Italy | Archdiocese of Cosenza–Bisignano was promoted as Metropolitan Archdiocese of Cosenza–Bisignano (with suffragan sees Rossano–Cariati, Cassano all’Jonio and San Marco Argentano–Scalea) |
| 2001.02.03 |  Paraguay | Diocese of Alto Paraná was renamed as Diocese of Ciudad del Este |
| 2001.02.16 |  USA | Diocese of Saint Thomas the Apostle of Chicago (Syro-Malabar Rite) was established (without ecclesiastical province) |
| 2001.03.13 |  Guinea-Bissau | Diocese of Bafatá was established (from Diocese of Bissau and without ecclesiastical province) |
| 2001.03.13 |  Niger | Diocese of Maradi was established (from Diocese of Niamey and without ecclesiastical province) |
| 2001.04.24 |  Argentina | Diocese of Avellaneda was renamed as Diocese of Avellaneda–Lanús (gained territory from Diocese of Lomas de Zamora) |
| 2001.04.24 | Argentina | Diocese of Lomas de Zamora lost territory to Diocese of Avellaneda–Lanús |
| 2001.04.25 | Brazil | Diocese of Montes Claros was promoted as Metropolitan Archdiocese of Montes Claros (with suffragan sees Janaúba, Januária and Paracatu) |
| 2001.04.27 | Italy | Diocese of Cremona lost territory to Diocese of Crema |
| 2001.06.22 |  Venezuela | Apostolic Exarchate of Venezuela (Syriac Rite) was established |
| 2001.06.30 |  Kenya | Diocese of Maralal was established (from Diocese of Marsabit and became suffragan of Nyeri) |
| 2001.07.06 |  Peru | Territorial Prelature of Yauyos lost territory to Diocese of Chosica |
| 2001.07.19 | Brazil | Diocese of Bacabal lost territory to Diocese of Coroatá |
| 2001.10.16 |  India | Diocese of Visakhapatnam was promoted as Metropolitan Archdiocese of Visakhapatnam (with suffragan sees Eluru, Guntur, Nellore, Srikakulam and Vijayawada) |
| 2001.10.27 |  Moldova | Apostolic Administration of Moldova was promoted as Diocese of Chişinău (without ecclesiastical province) |
| 2001.11.09 |  Angola | Diocese of Dundo was established (from Diocese of Saurimo and became suffragan of Luanda) |
| 2001.11.09 |  Nigeria | Diocese of Nnewi was established (from Metropolitan Archdiocese of Onitsha and became suffragan of Onitsha) |
| 2001.11.09 |  Pakistan | Apostolic Prefecture of Quetta was established (from Metropolitan Archdiocese of Karachi and Diocese of Hyderabad) |
| 2001.12.01 |  Chad | Apostolic Prefecture of Mongo was established (from Metropolitan Archdiocese of N’Djaména and Diocese of Sarh) |
| 2001.12.22 |  Ghana | Diocese of Kumasi was promoted as Metropolitan Archdiocese of Kumasi (with suffragan sees Goaso, Konongo–Mampong, Obuasi and Sunyani) |
| 2001.12.22 |  Indonesia | Diocese of Tanjung Selor was established (from Diocese of Samarinda and became suffragan of Pontianak) |
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