| Date | Country | Change |
| 1843.03.21 | Mission sui juris of Tunis was promoted as Apostolic Vicariate of Tunis | |
| 1843.06.02 | Diocese of Maynas was renamed as Diocese of Chachapoyas | |
| 1843.08.11 | Diocese of Pittsburgh was established (from Diocese of Philadelphia and became suffragan of Baltimore) | |
| 1843.11.28 | Diocese of Chicago was established (from Diocese of Saint Louis and Diocese of Vincennes and became suffragan of Baltimore) | |
| 1843.11.28 | Diocese of Hartford was established (from Diocese of Boston and became suffragan of Baltimore) | |
| 1843.11.28 | Diocese of Little Rock was established (from Diocese of Saint Louis and became suffragan of Baltimore) | |
| 1843.11.28 | Diocese of Milwaukee was established (from Diocese of Detroit and became suffragan of Baltimore) | |
| 1843.12.01 | Apostolic Vicariate of Oregon was established (from Metropolitan Archdiocese of Baltimore and Archdiocese of Québec) |
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