| Date | Country | Change |
| 1842 | Diocese of Marasc (Armenian Rite) was established | |
| 1842.01.22 | Apostolic Prefecture of Deux Guinées et Sénégambie was established (from Diocese of Funchal and Diocese of Tomé) | |
| 1842.02.15 | Apostolic Vicariate of Nova Scotia was promoted as Diocese of Halifax | |
| 1842.04.05 | Apostolic Vicariate of Adelaide was established (from Apostolic Vicariate of New Holland and Van Diemen’s Land) | |
| 1842.04.05 | Apostolic Vicariate of Hobart was established (from Apostolic Vicariate of New Holland and Van Diemen’s Land) | |
| 1842.04.05 | Apostolic Vicariate of New Holland and Van Diemen’s Land was renamed as Apostolic Vicariate of Sydney (lost territory to establish Apostolic Vicariate of Adelaide and Apostolic Vicariate of Hobart) | |
| 1842.04.22 | Apostolic Vicariate of Adelaide was promoted as Diocese of Adelaide (became suffragan of Sydney) | |
| 1842.04.22 | Apostolic Vicariate of Hobart was promoted as Diocese of Hobart (became suffragan of Sydney) | |
| 1842.04.22 | Apostolic Vicariate of Sydney was promoted as Metropolitan Archdiocese of Sydney (with suffragan sees Adelaide and Hobart) | |
| 1842.05.18 | Diocese of Liège exchanged territory with Diocese of Namur | |
| 1842.05.18 | Diocese of Namur exchanged territory with Diocese of Liège | |
| 1842.08.23 | Apostolic Vicariate of Western Oceania was renamed as Apostolic Vicariate of New Zealand (lost territory to establish Apostolic Vicariate of Central Oceania) | |
| 1842.08.23 | Apostolic Vicariate of Central Oceania was established (from Apostolic Vicariate of Western Oceania) | |
| 1842.08.30 | Apostolic Prefecture of Mardin was established (from Apostolic Prefecture of Syria and Cilicia) | |
| 1842.09.12 | Apostolic Prefecture of Dutch Guyana–Suriname was promoted as Apostolic Vicariate of Dutch Guyana–Suriname | |
| 1842.09.20 | Apostolic Prefecture of Curaçao was promoted as Apostolic Vicariate of Curaçao | |
| 1842.09.28 | Diocese of San Salvador was established (from Metropolitan Archdiocese of Guatemala and became suffragan of Guatemala) | |
| 1842.09.30 | Diocese of Saint John in America was established (from Diocese of Charlottetown) | |
| 1842.10.03 | Apostolic Prefecture of Deux Guinées et Sénégambie was promoted as Apostolic Vicariate of Deux Guinées et Sénégambie |
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