| Date | Country | Change |
| 1900 | Mission sui juris of Lunda was established (from Apostolic Prefecture of Lower Congo in Cubango) | |
| 1900 | Titular Episcopal See of Nemesi was suppressed | |
| 1900 | Titular Episcopal See of Lacedæmon was promoted as Titular Archiepiscopal See of Lacedæmon | |
| 1900 | Titular Episcopal See of Tripolis in Libanum (Syriac Rite) was suppressed | |
| 1900 | Titular Episcopal See of Sabrata was restored | |
| 1900 | Titular Metropolitan See of Dioclea was restored | |
| 1900 | Titular Episcopal See of Attalia was promoted as Titular Archiepiscopal See of Attalia | |
| 1900 | Titular Episcopal See of Hypsus was renamed as Titular Episcopal See of Ipsus | |
| 1900 | Titular Episcopal See of Phocæa was restored | |
| 1900 | Titular Episcopal See of Polybotus was restored | |
| 1900 | Titular Episcopal See of Pompeiopolis was promoted as Titular Archiepiscopal See of Pompeiopolis | |
| 1900.01.05 | Apostolic Prefecture of San Domingo de Urubamba was established (from Diocese of Cusco) | |
| 1900.01.26 | Diocese of Saïdā (Maronite Rite) was restored (from Diocese of Tyr and Saïdā and without ecclesiastical province) | |
| 1900.01.26 | Diocese of Tyr and Saïdā (Maronite Rite) was renamed as Diocese of Tyr (lost territory to establish Diocese of Saïdā) | |
| 1900.02.05 | Apostolic Prefecture of San León del Amazonas was established (from Diocese of Chachapoyas) | |
| 1900.02.05 | Apostolic Prefecture of Ucayali was established (from Diocese of Ayacucho and Diocese of Huánuco) | |
| 1900.04.11 | Diocese of Manizales was established (from Diocese of Medellín and Diocese of Popayán) | |
| 1900.05.20 | Diocese of Garzón was established (from the suppressed Diocese of Tolima) | |
| 1900.05.20 | Diocese of Ibagué was established (from the suppressed Diocese of Tolima and became suffragan of Bogotá in Colombia) | |
| 1900.05.20 | Diocese of Tolima was suppressed (to Diocese of Popayán and to establish Diocese of Garzón and Diocese of Ibagué) | |
| 1900.06.13 | Diocese of Grafton was renamed as Diocese of Lismore | |
| 1900.06.20 | Diocese of Cartagena was promoted as Metropolitan Archdiocese of Cartagena (with suffragan sees Panamá and Santa Marta) | |
| 1900.06.20 | Diocese of Popayán was promoted as Metropolitan Archdiocese of Popayán (with suffragan sees Garzón, Manizales and Pasto) | |
| 1900.07.02 | Diocese of Alagôas was established (from Diocese of Olinda and became suffragan of São Salvador da Bahia) | |
| 1900.08.04 | Diocese of Pouso Alegre was established (from Diocese of Mariana and Diocese of São Paulo and became suffragan of São Sebastião do Rio de Janeiro) |
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