Jurisdiction: Diocese of Des Moines
Type: 
Cathedral
Rite: Roman (Latin)
Lists: Historic Catholic Churches in USA, Jubilee Churches in the Extraordinary Jubilee of Mercy (2016), Jubilee Churches in the Holy Year 2025
History: 1856
Patron: St. Ambrose
Location: 86H8H9QF+CM 
Address: 607 High St., Des Moines, Iowa 50309
Country: USA 
Telephone: +1 (515) 288-7411
GCatholic Church ID: 1998
Bishop: 
Bishop William Michael Joensen (65)
Basilica of St. John the Apostle, Des Moines (2.0 km ↖) Basilica of the Immaculate Conception, Conception, Missouri (170 km ↙) 
Church of St. Frances Cabrini, Omaha, Nebraska (200 km ←) Cathedral of St. Cecilia, Omaha, Nebraska (200 km ←) 
Co-Cathedral of St. Joseph, St. Joseph, Missouri (230 km ↙) Basilica of St. Francis Xavier, Dyersville (230 km ↗) Cathedral of the Epiphany, Sioux City (250 km ↖) Sacred Heart Cathedral, Davenport (250 km →) St. Raphael Cathedral, Dubuque (260 km ↗) Cathedral of the Risen Lord, Lincoln, Nebraska (270 km ←) 
Church of St. Anthony, Des Moines (1.9 km ↓) 
Church of Our Lady of the Americas, Des Moines (2.2 km ↗) St. Catherine of Siena Catholic Student Center, Des Moines (2.7 km ↖) St. Peter Vietnamese Community, Des Moines (3.3 km →) Church of St. Augustin, Des Moines (4.0 km ←) Church of the Holy Trinity, Des Moines (5.5 km ↖) Church of St. Theresa of the Child Jesus, Des Moines (6.2 km ←) Church of Christ the King, Des Moines (6.3 km ↓) Church of St. Joseph, Des Moines (6.8 km ↗) Church of All Saints, Des Moines (7.6 km ↑) Last updated on 2025.12.21
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