| Consistory of 1566.03.06 (at the time of creation) (1) |
| 1. |   Fr. Michele Bonelli, O.P. (24) | Cardinal-Priest |
| Consistory of 1568.03.24 (at the time of creation) (4) |
| 1. |   Fr. Diego Espinosa y Arévalo (65), Grand Inquisitor of Commission of Roman and Universal Inquisition | Cardinal-Priest |
| 2. |   Abbot Jérôme Souchier, O. Cist. (60), Abbot General of Order of Cistercians (Cistercians) | Cardinal-Priest |
| 3. | Mr. Gianpaolo Della Chiesa (47) | Cardinal-Deacon |
| 4. | Fr. Antonio Carafa (30) | Cardinal-Deacon |
| Consistory of 1570.05.17 (at the time of creation) (16) |
| 1. |  Archbishop Marco Antonio Maffei (48), Metropolitan Archbishop emeritus of Chieti (Italy) and Datary of His Holiness emeritus of Apostolic Dataria | Cardinal-Priest |
| 2. |  Archbishop Gaspar Cervantes de Gaete (59), Metropolitan Archbishop of Tarragona (Spain) | Cardinal-Priest |
| 3. | Archbishop Giulio Antonio Santorio (37), Metropolitan Archbishop of Santa Severina (Italy) and Apostolic Administrator of San Leone (Italy) | Cardinal-Priest |
| 4. | Fr. Pierdonato Cesi (49), former Apostolic Administrator of Narni (Italy) | Cardinal-Priest |
| 5. |  Bishop Carlo Grassi (50), Bishop of Corneto (Italy), Bishop of Montefiascone (Italy) and Vice-Camerlengo of the Holy Roman Church of Reverend Apostolic Camera | Cardinal-Priest |
| 6. | Bishop Charles d’Angennes de Rambouillet (39), Bishop of Le Mans (France) | Cardinal-Priest |
| 7. | Bishop Felice Peretti, O.F.M. Conv. (48), Bishop of Sant’Agata de’ Goti (Italy) | Cardinal-Priest |
| 8. | Bishop Giovanni Aldobrandini (45), Bishop of Imola (Italy) | Cardinal-Priest |
| 9. | Fr. Girolamo Rusticucci (33) | Cardinal-Priest |
| 10. | Mr. Giulio Acquaviva d’Aragona (24) | Cardinal-Deacon |
| 11. | Archbishop Gaspar de Zúñiga y Avellaneda (63), Metropolitan Archbishop of Sevilla (Spain) | Cardinal-Priest |
| 12. | Archbishop Nicolas de Pellevé (54), Metropolitan Archbishop of Sens (France) | Cardinal-Priest |
| 13. | Bishop Archangelo de’ Bianchi, O.P. (53), Bishop of Teano (Italy) | Cardinal-Priest |
| 14. | Bishop Paolo Burali d’Arezzo, C.R. (59), Bishop of Piacenza (Italy) | Cardinal-Priest |
| 15. |  Fr. Vincenzo Giustiniani, O.P. (50), Master of the Order of Order of Preachers (Dominicans) | Cardinal-Priest |
| 16. | Mr. Gian Girolamo Albani (66) | Cardinal-Priest |
(21)
