- 100?: Established as Diocese of Ptolemais (latine) / Tolemaide (Italiano)
- 600?: Suppressed
- 1800: Restored as Titular Episcopal See of Ptolemais (latine) / Tolemaide (Italiano)
- 1870?: Gained territory from the suppressed Titular Episcopal See of Akka
- 1895?: Suppressed
- 1909: Restored as Titular Archiepiscopal See of Ptolemais (latine) / Tolemaide (Italiano)
- 1925: Demoted as Titular Episcopal See of Ptolemais (latine) / Tolemaide (Italiano)
- 1926: Renamed as Titular Episcopal See of Ptolemais (latine) / Tolemaide di Fenicia (Italiano)
- 1933: Renamed as Titular Episcopal See of Ptolemais in Phœnicia (latine) / Tolemaide di Fenicia (Italiano) / Ptolemaiden(sis) in Phœnicia (Latin)