| Date | Country | Change |
| 1978 | Diocese of Ascoli Satriano exchanged territory with Diocese of Bovino | |
| 1978 | Diocese of Bovino exchanged territory with Diocese of Ascoli Satriano | |
| 1978 | Archdiocese of Cosenza lost territory to Diocese of Lungro | |
| 1978 | Apostolic Administration of Szatmár na Slovensku was suppressed (to Diocese of Satu Mare) | |
| 1978.01.03 | Territorial Prelature of Coxim was established (from Diocese of Campo Grande and became suffragan of Cuiabá) | |
| 1978.01.03 | Diocese of Três Lagoas was established (from Diocese of Campo Grande and became suffragan of Cuiabá) | |
| 1978.01.03 | Territorial Prelature of Vila Rondônia was established (from Territorial Prelature of Guajará-Mirim and Territorial Prelature of Porto Velho and became suffragan of Manaus) | |
| 1978.01.16 | Diocese of Mao–Monte Cristi was established (from Diocese of Santiago de los Caballeros) | |
| 1978.01.16 | Diocese of San Francisco de Macorís was established (from Diocese of La Vega and Diocese of Santiago de los Caballeros) | |
| 1978.01.16 | Diocese of Santiago de los Caballeros lost territory to Diocese of La Vega | |
| 1978.01.18 | Diocese of Rottenburg was renamed as Diocese of Rottenburg–Stuttgart | |
| 1978.01.30 | Apostolic Prefecture of Lodwar was promoted as Diocese of Lodwar (became suffragan of Nairobi) | |
| 1978.02.27 | Diocese of Bouar was established (from Diocese of Berbérati and became suffragan of Bangui) | |
| 1978.02.27 | Diocese of Kakamega was established (from Diocese of Kisumu and became suffragan of Nairobi) | |
| 1978.02.27 | Apostolic Prefecture of Western Transvaal was promoted as Diocese of Klerksdorp (became suffragan of Pretoria) | |
| 1978.04.24 | Apostolic Exarchate of Argentina (Ukrainian Rite) was promoted as Diocese of Santa María del Patrocinio en Buenos Aires (became suffragan of Buenos Aires) | |
| 1978.05.05 | Diocese of Cascavel was established (from Diocese of Toledo and became suffragan of Curitiba) | |
| 1978.05.05 | Diocese of Foz do Iguaçu was restored (from Diocese of Toledo and became suffragan of Curitiba) | |
| 1978.05.14 | Diocese of Massa Marittima e Populonia was renamed as Diocese of Massa Marittima–Piombino | |
| 1978.05.14 | Titular Episcopal See of Populonia was restored | |
| 1978.05.23 | Metropolitan Archdiocese of Milano (Ambrosian Rite) lost territory to Diocese of Lodi | |
| 1978.05.31 | Apostolic Administration of Český Těšín was suppressed (to Metropolitan Archdiocese of Olomouc) | |
| 1978.05.31 | Metropolitan Archdiocese of Wrocław lost territory to Metropolitan Archdiocese of Olomouc | |
| 1978.06.05 | Diocese of Carapeguá was established (from Diocese of Villarrica and became suffragan of Asunción) | |
| 1978.06.05 | Diocese of San Pedro was established (from Diocese of Concepción and became suffragan of Asunción) | |
| 1978.06.08 | Diocese of Raiganj was established (from Diocese of Dumka and became suffragan of Calcutta) | |
| 1978.06.22 | Diocese of Irinjalakuda (Syro-Malabar Rite) was established (from Diocese of Trichur and became suffragan of Ernakulam) | |
| 1978.07.11 | Diocese of San Miguel was established (from Diocese of San Martín and became suffragan of Buenos Aires) | |
| 1978.07.14 | Diocese of San Bernardino was established (from Diocese of San Diego and became suffragan of Los Angeles) | |
| 1978.10.28 | Diocese of Bathery (Syro-Malankara Rite) was established (from Diocese of Tiruvalla and became suffragan of Trivandrum) | |
| 1978.11.07 | Diocese of Itabuna was established (from Diocese of Ilhéus and became suffragan of São Salvador da Bahia) | |
| 1978.11.07 | Diocese of Jequié was established (from Diocese of Amargosa and Diocese of Vitória da Conquista and became suffragan of São Salvador da Bahia) | |
| 1978.11.15 | Diocese of Tarawa was renamed as Diocese of Tarawa, Nauru and Funafuti | |
| 1978.11.15 | Diocese of Honiara was promoted as Metropolitan Archdiocese of Honiara (with suffragan see Gizo) | |
| 1978.11.21 | Diocese of Arezzo lost territory to Metropolitan Archdiocese of Siena | |
| 1978.11.27 | Diocese of Campo Grande was promoted as Metropolitan Archdiocese of Campo Grande (with suffragan sees Corumbá, Dourados, Três Lagoas and Coxim) | |
| 1978.12.09 | Diocese of Tandag was established (from Diocese of Surigao and became suffragan of Cagayan de Oro) |
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